Viral factors that facilitate HIV transmission

New insight into viral factors that facilitate HIV transmission

LANL scientists found that the infected donor’s predominant virus subpopulation in the genital tract differed from that in the blood. Comparing the HIV sequence population in each newly infected partner with that in the genital tract of the transmitting partner revealed that the transmitted variant was genetically distinct from the donor’s predominant genital-tract variants. The results imply that a selective process, rather than a random one, determines the transmitted or founder virus.

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